Comparison of inhibition of Escherichia coli topoisomerase IV by quinolones with DNA gyrase inhibition.

In order to examine the inhibitory activities of quinolones against topoisomerase IV, both subunits of this enzyme, ParC and ParE, were purified from Escherichia coli. The specific activity of topoisomerase IV decatenation was found to be more than five times greater than that of topoisomerase IV re...

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Détails bibliographiques

Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Hoshino, K, Kitamura, A, Morrissey, I, Sato, K, Kato, J, Ikeda, H
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1994
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188252/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7872758/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.11.2623
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