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Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity
There are many sources of genetic diversity, ranging from programmed mutagenesis in antibody genes to random mutagenesis during species evolution or development of cancer. We propose that mutations in DNA sequence-specific transcription factors that target response elements (REs) in many genes can a...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC187891/ https://ncbi.nlm.nih.gov/pubmed/12909720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1633803100 |
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