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A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network
The VEGF system is essential for angiogenesis. VEGF overexpression frequently correlates with increased microvascularity and metastasis and decreased spontaneous apoptosis. Although a precise mechanism has not been established, studies suggest that VEGF expression is negatively regulated by p53, a m...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1360546/ https://ncbi.nlm.nih.gov/pubmed/16432214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508103103 |
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