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A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network
The VEGF system is essential for angiogenesis. VEGF overexpression frequently correlates with increased microvascularity and metastasis and decreased spontaneous apoptosis. Although a precise mechanism has not been established, studies suggest that VEGF expression is negatively regulated by p53, a m...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1360546/ https://ncbi.nlm.nih.gov/pubmed/16432214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508103103 |
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