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Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation
The p53 tumor suppressor protein is a master regulatory transcription factor that coordinates cellular responses to DNA damage and cellular stress. Besides mutations in p53, or in proteins involved in the p53 response pathway, genetic variation in promoter response elements (REs) of p53 target genes...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1088378/ https://ncbi.nlm.nih.gov/pubmed/15843459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501721102 |
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