PACT is a negative regulator of p53 and essential for cell growth and embryonic development

The tumor suppressor p53 regulates cell cycle progression and apoptosis in response to various types of stress, whereas excess p53 activity creates unwanted effects. Tight regulation of p53 is essential for maintaining normal cell growth. p53-associated cellular protein-testes derived (PACT, also kn...

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Bibliographic Details
Main Authors: Li, Li, Deng, Binwei, Xing, Guichun, Teng, Yan, Tian, Chunyan, Cheng, Xuan, Yin, Xiushan, Yang, Juntao, Gao, Xue, Zhu, Yunping, Sun, Qihong, Zhang, Lingqiang, Yang, Xiao, He, Fuchu
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876553/
https://ncbi.nlm.nih.gov/pubmed/17470788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701916104
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