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PACT is a negative regulator of p53 and essential for cell growth and embryonic development
The tumor suppressor p53 regulates cell cycle progression and apoptosis in response to various types of stress, whereas excess p53 activity creates unwanted effects. Tight regulation of p53 is essential for maintaining normal cell growth. p53-associated cellular protein-testes derived (PACT, also kn...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1876553/ https://ncbi.nlm.nih.gov/pubmed/17470788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701916104 |
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