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Acid–base catalysis in Leuconostoc mesenteroides sucrose phosphorylase probed by site-directed mutagenesis and detailed kinetic comparison of wild-type and Glu(237)→Gln mutant enzymes

The role of acid–base catalysis in the two-step enzymatic mechanism of α-retaining glucosyl transfer by Leuconostoc mesenteroides sucrose phosphorylase has been examined through site-directed replacement of the putative catalytic Glu(237) and detailed comparison of purified wild-type and Glu(237)→Gl...

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Hlavní autoři: Schwarz, Alexandra, Brecker, Lothar, Nidetzky, Bernd
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876375/
https://ncbi.nlm.nih.gov/pubmed/17233628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070042
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