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Diastereoselective Synthesis of Glycosyl Phosphates by Using a Phosphorylase–Phosphatase Combination Catalyst

Sugar phosphates play an important role in metabolism and signaling, but also as constituents of macromolecular structures. Selective phosphorylation of sugars is chemically difficult, particularly at the anomeric center. We report phosphatase‐catalyzed diastereoselective “anomeric” phosphorylation...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Wildberger, Patricia, Pfeiffer, Martin, Brecker, Lothar, Nidetzky, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY‐VCH Verlag 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737314/
https://ncbi.nlm.nih.gov/pubmed/26565075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201507710
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