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Diastereoselective Synthesis of Glycosyl Phosphates by Using a Phosphorylase–Phosphatase Combination Catalyst

Sugar phosphates play an important role in metabolism and signaling, but also as constituents of macromolecular structures. Selective phosphorylation of sugars is chemically difficult, particularly at the anomeric center. We report phosphatase‐catalyzed diastereoselective “anomeric” phosphorylation...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Wildberger, Patricia, Pfeiffer, Martin, Brecker, Lothar, Nidetzky, Bernd
Format: Artigo
Sprog:Inglês
Udgivet: WILEY‐VCH Verlag 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737314/
https://ncbi.nlm.nih.gov/pubmed/26565075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201507710
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