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Diastereoselective Synthesis of Glycosyl Phosphates by Using a Phosphorylase–Phosphatase Combination Catalyst

Sugar phosphates play an important role in metabolism and signaling, but also as constituents of macromolecular structures. Selective phosphorylation of sugars is chemically difficult, particularly at the anomeric center. We report phosphatase‐catalyzed diastereoselective “anomeric” phosphorylation...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Wildberger, Patricia, Pfeiffer, Martin, Brecker, Lothar, Nidetzky, Bernd
Format: Artigo
Idioma:Inglês
Publicat: WILEY‐VCH Verlag 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737314/
https://ncbi.nlm.nih.gov/pubmed/26565075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201507710
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