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Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice

Neurotrophin nerve growth factor (NGF) has been suggested to be involved in age-related neurodegenerative diseases, but no transgenic model is currently available to study this concept. We have obtained transgenic mice expressing a neutralizing anti-NGF recombinant antibody, in which the levels of a...

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Main Authors: Capsoni, Simona, Ugolini, Gabriele, Comparini, Alessandro, Ruberti, Francesca, Berardi, Nicoletta, Cattaneo, Antonino
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2000
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC18754/
https://ncbi.nlm.nih.gov/pubmed/10841577
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