Transgenic Mice with Chronic NGF Deprivation and Alzheimer's Disease-Like Pathology Display Hippocampal Region-Specific Impairments in Short- and Long-Term Plasticities

The etiology of Alzheimer's disease (AD) remains elusive. The “amyloid” hypothesis states that toxic action of accumulated β-amyloid peptide (Aβ) on synaptic function causes AD cognitive decline. This hypothesis is supported by analysis of familial AD (FAD)-based transgenic mouse models, where...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Houeland, Gry, Romani, Armando, Marchetti, Cristina, Amato, Gianluca, Capsoni, Simona, Cattaneo, Antonino, Marie, Hélène
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2010
Schlagworte:
Brief Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633528/
https://ncbi.nlm.nih.gov/pubmed/20881126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0457-10.2010
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge