Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice
Neurotrophin nerve growth factor (NGF) has been suggested to be involved in age-related neurodegenerative diseases, but no transgenic model is currently available to study this concept. We have obtained transgenic mice expressing a neutralizing anti-NGF recombinant antibody, in which the levels of a...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18754/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10841577/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.12.6826 |
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