Phenotypic Knockout of Nerve Growth Factor in Adult Transgenic Mice Reveals Severe Deficits in Basal Forebrain Cholinergic Neurons, Cell Death in the Spleen, and Skeletal Muscle Dystrophy

The disruption of the nerve growth factor (NGF) gene in transgenic mice leads to a lethal phenotype (Crowley et al., 1994) and hinders the study of NGF functions in the adult. In this study the phenotypic knockout of NGF in adult mice was achieved by expressing transgenic anti-NGF antibodies, under...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Ruberti, Francesca, Capsoni, Simona, Comparini, Alessandro, Di Daniel, Elena, Franzot, Jessica, Gonfloni, Stefania, Rossi, Gabriella, Berardi, Nicoletta, Cattaneo, Antonino
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2000
Onderwerpen:
ARTICLE
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772248/
https://ncbi.nlm.nih.gov/pubmed/10729339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-07-02589.2000
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items