Functional Blockade of Tyrosine Kinase A in the Rat Basal Forebrain by a Novel Antagonistic Anti-Receptor Monoclonal Antibody

We have exploited a new monoclonal antibody against the tyrosine kinase A (TrkA) nerve growth factor (NGF) receptor to block the NGF–TrkA interaction in the rat basal forebrain. The monoclonal antibody MNAC13 is a potent antagonist that prevents the binding of NGF to TrkA in a variety of systems. Th...

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Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Cattaneo, Antonino, Capsoni, Simona, Margotti, Elisa, Righi, Massimo, Kontsekova, Eva, Pavlik, Peter, Filipcik, Peter, Novak, Michal
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 1999
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ARTICLE
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782945/
https://ncbi.nlm.nih.gov/pubmed/10559378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-22-09687.1999
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