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Brain-Derived Neurotrophic Factor (BDNF) Induces Dendritic Targeting of BDNF and Tyrosine Kinase B mRNAs in Hippocampal Neurons through a Phosphatidylinositol-3 Kinase-Dependent Pathway

This study aims to understand the mechanisms of dendritic targeting of brain-derived neurotrophic factor (BDNF) and tyrosine kinase B (TrkB) mRNAs. We show that brief depolarizations are sufficient to induce accumulation of BDNF and TrkB mRNAs in dendrites of hippocampal neurons. Endogenous BDNF, se...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Righi, Massimo, Tongiorgi, Enrico, Cattaneo, Antonino
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773127/
https://ncbi.nlm.nih.gov/pubmed/10777780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-09-03165.2000
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