Functional Blockade of Tyrosine Kinase A in the Rat Basal Forebrain by a Novel Antagonistic Anti-Receptor Monoclonal Antibody

We have exploited a new monoclonal antibody against the tyrosine kinase A (TrkA) nerve growth factor (NGF) receptor to block the NGF–TrkA interaction in the rat basal forebrain. The monoclonal antibody MNAC13 is a potent antagonist that prevents the binding of NGF to TrkA in a variety of systems. Th...

Full description

Saved in:
Bibliographic Details
Published in:J Neurosci
Main Authors: Cattaneo, Antonino, Capsoni, Simona, Margotti, Elisa, Righi, Massimo, Kontsekova, Eva, Pavlik, Peter, Filipcik, Peter, Novak, Michal
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 1999
Subjects:
ARTICLE
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782945/
https://ncbi.nlm.nih.gov/pubmed/10559378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-22-09687.1999
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items