Intranasal delivery of BDNF rescues memory deficits in AD11 mice and reduces brain microgliosis

A decrease in brain-derived neurotrophic factor (BDNF), a neurotrophin essential for synaptic function, plasticity and neuronal survival, is evident early in the progression of Alzheimer’s disease (AD), being apparent in subjects with mild cognitive impairment or mild AD, and both proBDNF and mature...

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Detalhes bibliográficos
Publicado no:Aging Clin Exp Res
Main Authors: Braschi, Chiara, Capsoni, Simona, Narducci, Roberta, Poli, Andrea, Sansevero, Gabriele, Brandi, Rossella, Maffei, Lamberto, Cattaneo, Antonino, Berardi, Nicoletta
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081712/
https://ncbi.nlm.nih.gov/pubmed/32676979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40520-020-01646-5
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