CD44 is required for two consecutive steps in HGF/c-Met signaling

The tyrosine kinase receptor c-Met and its ligand HGF/SF, ezrin, and splice variants of CD44 have independently been identified as tumor metastasis-associated proteins. We now show that these proteins cooperate. A CD44 isoform containing variant exon v6 sequences is strictly required for c-Met activ...

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Autores principales: Orian-Rousseau, Véronique, Chen, Linfeng, Sleeman, Jonathan P., Herrlich, Peter, Ponta, Helmut
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2002
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC187488/
https://ncbi.nlm.nih.gov/pubmed/12464636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.242602
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