CD44 is required for two consecutive steps in HGF/c-Met signaling
The tyrosine kinase receptor c-Met and its ligand HGF/SF, ezrin, and splice variants of CD44 have independently been identified as tumor metastasis-associated proteins. We now show that these proteins cooperate. A CD44 isoform containing variant exon v6 sequences is strictly required for c-Met activ...
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| Pubblicato in: | Genes Dev |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187488/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12464636/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.242602 |
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