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CD44 is required for two consecutive steps in HGF/c-Met signaling
The tyrosine kinase receptor c-Met and its ligand HGF/SF, ezrin, and splice variants of CD44 have independently been identified as tumor metastasis-associated proteins. We now show that these proteins cooperate. A CD44 isoform containing variant exon v6 sequences is strictly required for c-Met activ...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC187488/ https://ncbi.nlm.nih.gov/pubmed/12464636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.242602 |
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