The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44

The neurofibromatosis-2 (NF2) gene encodes merlin, an ezrin-radixin-moesin-(ERM)-related protein that functions as a tumor suppressor. We found that merlin mediates contact inhibition of growth through signals from the extracellular matrix. At high cell density, merlin becomes hypo-phosphorylated an...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Morrison, Helen, Sherman, Larry S., Legg, James, Banine, Fatima, Isacke, Clare, Haipek, Carrie A., Gutmann, David H., Ponta, Helmut, Herrlich, Peter
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2001
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312675/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11316791/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.189601
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!