Increased amyloidogenic secretion in cerebellar granule cells undergoing apoptosis

Some clues suggest that neuronal damage induces a secondary change of amyloid β protein (Aβ) metabolism. We investigated this possibility by analyzing the secretion of Aβ and processing of its precursor protein (amyloid precursor protein, APP) in an in vitro model of neuronal apoptosis. Primary cult...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Galli, Cinzia, Piccini, Alessandra, Ciotti, Maria Teresa, Castellani, Loriana, Calissano, Pietro, Zaccheo, Damiano, Tabaton, Massimo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18734/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9448317/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.3.1247
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