Increased amyloidogenic secretion in cerebellar granule cells undergoing apoptosis

Some clues suggest that neuronal damage induces a secondary change of amyloid β protein (Aβ) metabolism. We investigated this possibility by analyzing the secretion of Aβ and processing of its precursor protein (amyloid precursor protein, APP) in an in vitro model of neuronal apoptosis. Primary cult...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Galli, Cinzia, Piccini, Alessandra, Ciotti, Maria Teresa, Castellani, Loriana, Calissano, Pietro, Zaccheo, Damiano, Tabaton, Massimo
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1998
Предметы:	Biological Sciences
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18734/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9448317/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.3.1247
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