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Increased amyloidogenic secretion in cerebellar granule cells undergoing apoptosis

Some clues suggest that neuronal damage induces a secondary change of amyloid β protein (Aβ) metabolism. We investigated this possibility by analyzing the secretion of Aβ and processing of its precursor protein (amyloid precursor protein, APP) in an in vitro model of neuronal apoptosis. Primary cult...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Galli, Cinzia, Piccini, Alessandra, Ciotti, Maria Teresa, Castellani, Loriana, Calissano, Pietro, Zaccheo, Damiano, Tabaton, Massimo
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18734/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9448317/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.3.1247
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