Increased amyloidogenic secretion in cerebellar granule cells undergoing apoptosis

Some clues suggest that neuronal damage induces a secondary change of amyloid β protein (Aβ) metabolism. We investigated this possibility by analyzing the secretion of Aβ and processing of its precursor protein (amyloid precursor protein, APP) in an in vitro model of neuronal apoptosis. Primary cult...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Galli, Cinzia, Piccini, Alessandra, Ciotti, Maria Teresa, Castellani, Loriana, Calissano, Pietro, Zaccheo, Damiano, Tabaton, Massimo
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1998
Subjects:	Biological Sciences
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18734/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9448317/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.3.1247
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