Coinjection with CpG-Containing Immunostimulatory Oligodeoxynucleotides Reduces the Pathogenicity of a Live Vaccine against Cutaneous Leishmaniasis but Maintains Its Potency and Durability

The inoculation of live, nonattenuated Leishmania major to produce a lesion in a selected site that heals, referred to as leishmanization, is to date the only vaccine against leishmaniasis that has proven to be effective in humans. Its use has been restricted or abandoned entirely, however, due to s...

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Vydáno v:	Infect Immun
Hlavní autoři:	Mendez, Susana, Tabbara, Khaled, Belkaid, Yasmine, Bertholet, Sylvie, Verthelyi, Daniela, Klinman, Dennis, Seder, Robert A., Sacks, David L.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2003
Témata:	Fungal and Parasitic Infections
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187328/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12933855/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.9.5121-5129.2003
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