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Coinjection with CpG-Containing Immunostimulatory Oligodeoxynucleotides Reduces the Pathogenicity of a Live Vaccine against Cutaneous Leishmaniasis but Maintains Its Potency and Durability

The inoculation of live, nonattenuated Leishmania major to produce a lesion in a selected site that heals, referred to as leishmanization, is to date the only vaccine against leishmaniasis that has proven to be effective in humans. Its use has been restricted or abandoned entirely, however, due to s...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Infect Immun
Principais autores: Mendez, Susana, Tabbara, Khaled, Belkaid, Yasmine, Bertholet, Sylvie, Verthelyi, Daniela, Klinman, Dennis, Seder, Robert A., Sacks, David L.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2003
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187328/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12933855/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.9.5121-5129.2003
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