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Coinjection with CpG-Containing Immunostimulatory Oligodeoxynucleotides Reduces the Pathogenicity of a Live Vaccine against Cutaneous Leishmaniasis but Maintains Its Potency and Durability

The inoculation of live, nonattenuated Leishmania major to produce a lesion in a selected site that heals, referred to as leishmanization, is to date the only vaccine against leishmaniasis that has proven to be effective in humans. Its use has been restricted or abandoned entirely, however, due to s...

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Sonraí Bibleagrafaíochta
Main Authors: Mendez, Susana, Tabbara, Khaled, Belkaid, Yasmine, Bertholet, Sylvie, Verthelyi, Daniela, Klinman, Dennis, Seder, Robert A., Sacks, David L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2003
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC187328/
https://ncbi.nlm.nih.gov/pubmed/12933855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.9.5121-5129.2003
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