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Direct and adaptor-mediated substrate recognition by an essential AAA+ protease

Regulated proteolysis is required to execute many cellular programs. In Caulobacter crescentus, timely degradation of the master regulator CtrA by ClpXP protease is essential for cell-cycle progression and requires the colocalization of CtrA and RcdA. Here, we establish a biochemical framework to un...

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Detalhes bibliográficos
Main Authors: Chien, Peter, Perchuk, Barrett S., Laub, Michael T., Sauer, Robert T., Baker, Tania A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871830/
https://ncbi.nlm.nih.gov/pubmed/17420450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701776104
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