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Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo

Activation of the inhibitor of NF-κB kinase/NF-κB (IKK/NF-κB) system and expression of proinflammatory mediators are major events in acute pancreatitis. However, the in vivo consequences of IKK activation on the onset and progression of acute pancreatitis remain unclear. Therefore, we modulated IKK...

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Detalhes bibliográficos
Main Authors: Baumann, Bernd, Wagner, Martin, Aleksic, Tamara, von Wichert, Götz, Weber, Christoph K., Adler, Guido, Wirth, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868787/
https://ncbi.nlm.nih.gov/pubmed/17525799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30876
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