Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo

Activation of the inhibitor of NF-κB kinase/NF-κB (IKK/NF-κB) system and expression of proinflammatory mediators are major events in acute pancreatitis. However, the in vivo consequences of IKK activation on the onset and progression of acute pancreatitis remain unclear. Therefore, we modulated IKK...

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Main Authors: Baumann, Bernd, Wagner, Martin, Aleksic, Tamara, von Wichert, Götz, Weber, Christoph K., Adler, Guido, Wirth, Thomas
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2007
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868787/
https://ncbi.nlm.nih.gov/pubmed/17525799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30876
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