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Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo
Activation of the inhibitor of NF-κB kinase/NF-κB (IKK/NF-κB) system and expression of proinflammatory mediators are major events in acute pancreatitis. However, the in vivo consequences of IKK activation on the onset and progression of acute pancreatitis remain unclear. Therefore, we modulated IKK...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1868787/ https://ncbi.nlm.nih.gov/pubmed/17525799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30876 |
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