Sustained, neuron-specific IKK/NF-κB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging

BACKGROUND: Increasing evidence indicates that neuroinflammation is a critical factor contributing to the progression of various neurodegenerative diseases. The IKK/NF-κB signalling system is a central regulator of inflammation, but it also affects neuronal survival and differentiation. A complex in...

Full description

Saved in:
Bibliographic Details
Main Authors: Maqbool, Ayesha, Lattke, Michael, Wirth, Thomas, Baumann, Bernd
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827934/
https://ncbi.nlm.nih.gov/pubmed/24119288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-8-40
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items