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Monoclonal antibody-mediated enhancement of dengue virus infection in vitro and in vivo and strategies for prevention
Infection with dengue virus (DENV) or any other flavivirus induces cross-reactive, but weakly neutralizing or nonneutralizing, antibodies that recognize epitopes involving the fusion peptide in the envelope glycoprotein. Humanized mAb IgG 1A5, derived from a chimpanzee, shares properties of cross-re...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1868655/ https://ncbi.nlm.nih.gov/pubmed/17517625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703498104 |
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