Intraneuronal Aβ42 Accumulation in Human Brain

Alzheimer’s disease (AD) is characterized by the deposition of senile plaques (SPs) and neurofibrillary tangles (NFTs) in vulnerable brain regions. SPs are composed of aggregated β-amyloid (Aβ) 40/42(43) peptides. Evidence implicates a central role for Aβ in the pathophysiology of AD. Mutations in β...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Gouras, Gunnar K., Tsai, Julia, Naslund, Jan, Vincent, Bruno, Edgar, Mark, Checler, Frederic, Greenfield, Jeffrey P., Haroutunian, Vahram, Buxbaum, Joseph D., Xu, Huaxi, Greengard, Paul, Relkin, Norman R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Investigative Pathology 2000
विषय:
Short Communications
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868613/
https://ncbi.nlm.nih.gov/pubmed/10623648
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