Wird geladen...

Intraneuronal Aβ42 Accumulation in Human Brain

Alzheimer’s disease (AD) is characterized by the deposition of senile plaques (SPs) and neurofibrillary tangles (NFTs) in vulnerable brain regions. SPs are composed of aggregated β-amyloid (Aβ) 40/42(43) peptides. Evidence implicates a central role for Aβ in the pathophysiology of AD. Mutations in β...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Gouras, Gunnar K., Tsai, Julia, Naslund, Jan, Vincent, Bruno, Edgar, Mark, Checler, Frederic, Greenfield, Jeffrey P., Haroutunian, Vahram, Buxbaum, Joseph D., Xu, Huaxi, Greengard, Paul, Relkin, Norman R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868613/
https://ncbi.nlm.nih.gov/pubmed/10623648
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!