Intraneuronal Alzheimer Aβ42 Accumulates in Multivesicular Bodies and Is Associated with Synaptic Pathology

A central question in Alzheimer’s disease concerns the mechanism by which β-amyloid contributes to neuropathology, and in particular whether intracellular versus extracellular β-amyloid plays a critical role. Alzheimer transgenic mouse studies demonstrate brain dysfunction, as β-amyloid levels rise,...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Takahashi, Reisuke H., Milner, Teresa A., Li, Feng, Nam, Ellen E., Edgar, Mark A., Yamaguchi, Haruyasu, Beal, M. Flint, Xu, Huaxi, Greengard, Paul, Gouras, Gunnar K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Investigative Pathology 2002
Aiheet:
Regular Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850783/
https://ncbi.nlm.nih.gov/pubmed/12414533
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