טוען...
Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer β-amyloid peptides
The excessive generation and accumulation of 40- and 42-aa β-amyloid peptides (Aβ(40)/Aβ(42)) in selectively vulnerable brain regions is a major neuropathological feature of Alzheimer’s disease. Aβ, derived by proteolytic cleavage from the β-amyloid precursor protein (βAPP), is normally secreted. Ho...
שמור ב:
| Main Authors: | , , , , , , , , |
|---|---|
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The National Academy of Sciences
1999
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC15207/ https://ncbi.nlm.nih.gov/pubmed/9892704 |
| תגים: |
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