Wordt geladen...
Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer β-amyloid peptides
The excessive generation and accumulation of 40- and 42-aa β-amyloid peptides (Aβ(40)/Aβ(42)) in selectively vulnerable brain regions is a major neuropathological feature of Alzheimer’s disease. Aβ, derived by proteolytic cleavage from the β-amyloid precursor protein (βAPP), is normally secreted. Ho...
Bewaard in:
| Hoofdauteurs: | , , , , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The National Academy of Sciences
1999
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC15207/ https://ncbi.nlm.nih.gov/pubmed/9892704 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|