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Pin1 in Alzheimer’s disease: multiple substrates, one regulatory mechanism?

Presence of neuritic plaques and neurofibrillary tangles in the brain are two neuropathological hallmarks of Alzheimer’s disease (AD), although the molecular basis of their coexistence remains elusive. The neurofibrillary tangles are composed of microtubule binding protein Tau, whereas neuritic plaq...

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Detalhes bibliográficos
Main Authors: Balastik, Martin, Lim, Jormay, Pastorino, Lucia, Lu, Kun Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868500/
https://ncbi.nlm.nih.gov/pubmed/17317113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2007.01.006
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