Essential role of Pin1 in regulation of TRF1 stability and telomere maintenance

Telomeres are essential for maintaining cellular proliferative capacity and their loss has been implicated in aging. A key regulator in telomere maintenance is the telomeric protein TRF1, which was also identified as Pin2 in a same screen for Pin1. Pin1 is a unique prolyl isomerase that regulates pr...

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Bibliografiske detaljer
Main Authors: Lee, Tae Ho, Tun-Kyi, Adrian, Shi, Rong, Lim, Jormay, Soohoo, Christina, Finn, Greg, Balastik, Martin, Pastorino, Lucia, Wulf, Gerburg, Zhou, Xiao Zhen, Lu, Kun Ping
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699942/
https://ncbi.nlm.nih.gov/pubmed/19060891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1818
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