Učitavanje...
Essential role of Pin1 in regulation of TRF1 stability and telomere maintenance
Telomeres are essential for maintaining cellular proliferative capacity and their loss has been implicated in aging. A key regulator in telomere maintenance is the telomeric protein TRF1, which was also identified as Pin2 in a same screen for Pin1. Pin1 is a unique prolyl isomerase that regulates pr...
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| Glavni autori: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2699942/ https://ncbi.nlm.nih.gov/pubmed/19060891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1818 |
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