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PinX1 Localizes to Telomeres and Stabilizes TRF1 at Mitosis

Human telomeres are DNA-protein complexes that cap and protect the ends of chromosomes. The protein PinX1 associates with telomeres through an interaction with the resident double-stranded telomere-binding protein TRF1. PinX1 also binds to and inhibits telomerase, the enzyme responsible for complete...

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Detalhes bibliográficos
Main Authors: Yonekawa, Tohru, Yang, Shuqun, Counter, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318592/
https://ncbi.nlm.nih.gov/pubmed/22331467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05641-11
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