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PinX1 the tail on the chromosome
The PinX1 protein inhibits telomerase, an enzyme that lengthens telomeres — the structures that protect the ends of chromosomes. Loss of PinX1 leads to increased telomere length along with defects in chromosome dynamics. In this issue of the JCI, Zhou et al. present novel evidence from human tumors...
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| Format: | Artigo |
| Jezik: | Inglês |
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American Society for Clinical Investigation
2011
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069792/ https://ncbi.nlm.nih.gov/pubmed/21436580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57024 |
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