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PinX1 the tail on the chromosome

The PinX1 protein inhibits telomerase, an enzyme that lengthens telomeres — the structures that protect the ends of chromosomes. Loss of PinX1 leads to increased telomere length along with defects in chromosome dynamics. In this issue of the JCI, Zhou et al. present novel evidence from human tumors...

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Bibliografiska uppgifter
Huvudupphovsman: Johnson, F. Brad
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069792/
https://ncbi.nlm.nih.gov/pubmed/21436580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57024
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