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Pin1 in Alzheimer’s disease: multiple substrates, one regulatory mechanism?

Presence of neuritic plaques and neurofibrillary tangles in the brain are two neuropathological hallmarks of Alzheimer’s disease (AD), although the molecular basis of their coexistence remains elusive. The neurofibrillary tangles are composed of microtubule binding protein Tau, whereas neuritic plaq...

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Hlavní autoři: Balastik, Martin, Lim, Jormay, Pastorino, Lucia, Lu, Kun Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868500/
https://ncbi.nlm.nih.gov/pubmed/17317113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2007.01.006
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