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Emphysematous Lesions, Inflammation, and Fibrosis in the Lungs of Transgenic Mice Overexpressing Platelet-Derived Growth Factor

Because of its expression pattern and its potent effects on mesenchymal cells, platelet-derived growth factor (PDGF) has been implicated as an important factor in epithelial-mesenchymal cell interactions during normal lung development and in the pathogenesis of fibrotic lung disease. To further expl...

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Detalhes bibliográficos
Main Authors: Hoyle, Gary W., Li, Jian, Finkelstein, Jeffrey B., Eisenberg, Todd, Liu, Jing-Yao, Lasky, Joseph A., Athas, Grace, Morris, Gilbert F., Brody, Arnold R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866633/
https://ncbi.nlm.nih.gov/pubmed/10362801
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