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Conditional overexpression of transgenes in megakaryocytes and platelets in vivo

Megakaryocyte (MK)–specific transgene expression has proved valuable in studying thrombotic and hemostatic processes. Constitutive expression of genes, however, could result in altered phenotypes due to compensatory mechanisms or lethality. To circumvent these limitations, we used the tetracycline/d...

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Detalhes bibliográficos
Main Authors: Nguyen, Hao G., Yu, Guangyao, Makitalo, Maria, Yang, Dan, Xie, Hou-Xiang, Jones, Matthew R., Ravid, Katya
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895218/
https://ncbi.nlm.nih.gov/pubmed/15890684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-02-0638
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