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Survivin overexpression alone does not alter megakaryocyte ploidy nor interfere with erythroid/megakaryocytic lineage development in transgenic mice

The level of survivin was reported to be scarce in mouse megakaryocytes (MKs) compared with erythroid cells. Considering this finding and previously reported in vitro data showing decreased MK ploidy upon retroviral-mediated overexpression of survivin, we sought to examine whether ectopic survivin e...

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Detalhes bibliográficos
Main Authors: McCrann, Donald J., Yezefski, Todd, Nguyen, Hao G., Papadantonakis, Nicholas, Liu, Hui, Wen, Qiang, Crispino, John D., Ravid, Katya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288720/
https://ncbi.nlm.nih.gov/pubmed/18245663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-11-122150
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