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Survivin overexpression alone does not alter megakaryocyte ploidy nor interfere with erythroid/megakaryocytic lineage development in transgenic mice

The level of survivin was reported to be scarce in mouse megakaryocytes (MKs) compared with erythroid cells. Considering this finding and previously reported in vitro data showing decreased MK ploidy upon retroviral-mediated overexpression of survivin, we sought to examine whether ectopic survivin e...

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Hlavní autoři: McCrann, Donald J., Yezefski, Todd, Nguyen, Hao G., Papadantonakis, Nicholas, Liu, Hui, Wen, Qiang, Crispino, John D., Ravid, Katya
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288720/
https://ncbi.nlm.nih.gov/pubmed/18245663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-11-122150
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