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Differential expression of NADPH oxidases in megakaryocytes and their role in polyploidy

Megakaryocytes (MKs) undergo an endomitotic cell cycle, leading to polyploidy. We examined the expression of the flavoproteins and oxidative stress-promoting enzymes, NADPH oxidases (Nox's), in MKs because of their known role in promoting the cell cycle. Although the expression of Nox isoforms...

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Autors principals: McCrann, Donald J., Eliades, Alexia, Makitalo, Maria, Matsuno, Kuniharu, Ravid, Katya
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723018/
https://ncbi.nlm.nih.gov/pubmed/19471020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-195883
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